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Tao, Y., et al

And this is exactly where the problem begins

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As oxidative stress increases, further stimulation of pro-inflammatory cytokines such as TNF- and IL-1 increases and contributes to synaptic dysfunction and neuronal degeneration ( These studies suggest that the loss of antioxidant defense is an early biochemical event rather than a late-stage consequence of neuronal death

Sources: Clinical Nutrition ESPEN (2020)

When other symptoms, such as itching, redness, and inflammation on the scalp, or hair loss, accompany the greying of hair